Nabilone could treat chorea and irritability in Huntington's disease.
نویسندگان
چکیده
ory was relatively intact. On discharge, Mr. A continued to show improvement in his cognitive functions, and 2 months after the onset of NMS, his score on MMSE was 25/30 with persistent deficits in immediate and recent memory. He still had retrograde amnesia about the events surrounding the NMS and also had anterograde amnesia with deficits in learning new verbal information. Again, no deficits were noted in remote memory.
منابع مشابه
Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology.
OBJECTIVE To develop an evidence-based guideline assessing pharmacologic options for treating Huntington disease (HD) chorea. METHODS We evaluated available evidence from a structured literature review performed through February 2011. RESULTS AND RECOMMENDATIONS If HD chorea requires treatment, clinicians should prescribe tetrabenazine (up to 100 mg/day), amantadine (300-400 mg/day), or ril...
متن کاملNeuropsychiatric aspects of Huntington's disease.
OBJECTIVE Neuropsychiatric symptoms are common in Huntington's disease and have been considered its presenting manifestation. Research characterising these symptoms in Huntington's disease is variable, however, encumbered by limitations within and across studies. Gaining a better understanding of neuropsychiatric symptoms is essential, as these symptoms have implications for disease management,...
متن کاملRevisiting the neuropsychiatry of Huntington's disease
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease classified under the choreas. Besides motor symptoms, HD is marked by cognitive and behavioral symptoms, impacting patients' functional capacity. The progression of cognitive impairment and neuropsychiatric symptoms occur in parallel with neurodegeneration. The nature of these symptoms is very dynamic, and the major cl...
متن کاملA clinico-genetic study of psychiatric disorder in Huntington's chorea.
The introduction in 1985 of a genetic linkage test programme to identify asymptomatic heterozygotes among subjects at 50% initial risk for Huntington's chorea required a review of all cases of Huntington's chorea and their families referred to the Department of Medical Genetics of the Oxford Regional Health Area (population 2.5 million). From a representative sample of these subjects, psychiatr...
متن کاملNeuropsychiatric Burden in Huntington’s Disease
Huntington's disease is a disorder that results in motor, cognitive, and psychiatric problems. The symptoms often take different forms and the presence of disturbances of the psychic sphere reduces patients' autonomy and quality of life, also impacting patients' social life. It is estimated that a prevalence between 33% and 76% of the main psychiatric syndromes may arise in different phases of ...
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عنوان ژورنال:
- The Journal of neuropsychiatry and clinical neurosciences
دوره 18 4 شماره
صفحات -
تاریخ انتشار 2006